Chiron

Chiron · Chiron Structure Repair Server

Rapid Structure
Repair & Validation

Chiron rapidly minimizes steric clashes in protein structures using short discrete molecular dynamics (DMD) simulations. Gaia evaluates the quality of a given protein structure based on multiple criteria benchmarked against high-resolution crystal structures. Both tools are developed by the Dokholyan Lab.

Chiron — Minimize ClashesGaia — Validate Structure

Most jobs complete in minutes

Chiron

Chiron

Resolve steric clashes with short DMD simulations while preserving backbone conformation.

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Gaia

Evaluate quality across clashes, hydrogen bonds, voids, geometry, and side chains.

Launch
PDB ID or file upload → Chiron or Gaia → Results in minutes[email protected]